Non refundable honeymoon cruise, toxic job, and job search

I currently work in a county position, but the environment has become very toxic and hostile, and it’s seriously affecting my mental health. I’ve tried multiple times to transfer internally without su

I currently work in a county position, but the environment has become very toxic and hostile, and it’s seriously affecting my mental health. I’ve tried multiple times to transfer internally without success, so I’ve decided to leave the government work and start looking for outside positions that align with my bachelor’s degree in psychology. One concern I have during the job search is a non-refundable honeymoon cruise that my husband and I booked before the issues at work started. I’m completely open to taking the time off unpaid if needed. My goal is to hold on at my current job until June and resign before the cruise, but the situation at work has become very difficult to tolerate. I’m unsure when the best time would be to mention the honeymoon to a potential employer—whether during the phone screening, in the in-person interview, or later in the hiring process.